Chromosome breaking effect of a gasoline additive in cultured human lymphocytes
نویسندگان
چکیده
منابع مشابه
Determination of dose-response relationship in cultured human lymphocytes for biological dosimetry
Background: Lymphocyte-dicentric assay is the most generally accepted method for biological dosimetry of overexposed individuals. In this study, the frequency of unstable chromosome aberration in blood lymphocytes was used to estimate radiation dose received by individuals. Evaluation of dose using a calibration curve produced elsewhere may have a significant uncertainty therefore, experiments ...
متن کاملInhibition of repair of radiation-induced chromosome breaks: effects of chromium trioxide on cultured human lymphocytes.
MATERIALS AND METHODS Chromium is known to be an essential element1. Epidemiological and experimental studies have, however, demonstrated that some chromium compouds (mainly hexavalent salts) are mutagenic carcinogens2-5) (see ref. 1 for review). Recent studies have also shown that the hexavalent compounds induce dose-related increases in chromosomal aberrations and sister chromatid exchanges i...
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The naturally occurring polyamines, putrescine, spermidine and spermine, have been implicated in many growth processes and in differentiation (Cohen, 1971; Bachrach, 1973; Russell & Durie, 1978). Their concentrations and the activity of their biosynthetic enzymes increase significantly in proliferating cells (Tabor & Tabor, 1976; Janne & Raina, 1968) and neoplastic tissues (Bachrach, 1978; Russ...
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چکیده ندارد.
15 صفحه اولRadiation-induced chromosome damage in human lymphocytes.
Analysis for chromosome aberrations in human peripheral blood lymphocytes has been developed as an indicator of dose from ionising radiation. This paper outlines the mechanism of production of aberrations, the technique for their analysis and the dose-effect relationships for various types of radiation. During the past ten years the National Radiological Protection Board has developed a service...
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ژورنال
عنوان ژورنال: Hereditas
سال: 2009
ISSN: 0018-0661
DOI: 10.1111/j.1601-5223.1972.tb01030.x